NMN is the abbreviation of Nicotinamide mononucleotide, with a molecular weight of 334.2192. It is an inherent substance in the human body and is also rich in some fruits and vegetables. In the human body, NMN is the precursor of NAD+, and its function is reflected by NAD+.
NMN is a precursor of NAD+
NAD+ is also known as coenzyme I, the full name of nicotinamide adenine dinucleotide, also known as nicotinic acid diphosphate, exists in every cell and participates in thousands of reactions. NAD+ is an important coenzyme in the tricarboxylic acid cycle, promoting the metabolism of sugar, fat, and Amino Acids, and participating in the synthesis of energy; NAD+ is also the only substrate for coenzyme I consumption enzymes (the only substrate for the DNA repair enzyme PARP, the only substrate for the longevity protein Sirtuins) Substrate, the only substrate for cyclic ADP ribose synthase CD38/157).
The main effects of NAD+ on the human body
The tricarboxylic acid cycle is the final metabolic pathway of the three major nutrients (carbohydrates, lipids, and amino acids) in the human body, and it is also the hub of carbohydrates, lipids, and Amino Acid metabolism. The tricarboxylic acid cycle provides more than 95% of the energy in the body. It is the energy hub of the living body.
NAD+ levels decrease with age
NAD+ has a fundamental impact on human health, but with age, the content of NAD+ in the human body gradually decreases, the communication between mitochondria and nucleus is impaired, and the reduction of NAD+ also impairs the ability of cells to generate energy, resulting in Aging and disease, which may also be why we age.
Important health effects of NMN
1. Substance and energy metabolism
2. Prevent age-related physical decline
3. Improve type 2 diabetes
4. Prevention of neurodegenerative diseases (Parkinson's, Alzheimer's)
